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. 2019 Mar 26;10:235. doi: 10.3389/fgene.2019.00235

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Copyright © 2019 Verma, Shukla, Pandey, MacLennan and Gupta.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histology of dorsolateral prostate of TRAMP mice and non-transgenic littermates. Representative staining image of histopathology of 20 week old TRAMP mice and non-transgenic littermate. A typical dorsolateral prostate from a non-transgenic mouse exhibited acini with abundant eosinophilic intraluminal secretions. TRAMP mouse exhibited adenocarcinoma with extensive epithelial stratification, crowded cribriform structures accompanied with marked thickening, remodeling and hypercellularity of the fibromuscular stroma. (Magnification x20 and x40).