Table 1.
Detailed list of gene sets significantly enriched in microarray gene expression.
| Gene name | Non-transgenic mice (log2) | TRAMP mice (log2) | TRAMP vs. Non-transgenic log2 fold change | Differential regulation status |
|---|---|---|---|---|
| TGM4 | 8.067576 | 6.095323 | −1.972253 | DOWNREG IN TRAMP |
| SOSTDC1 | 6.28833 | 5.377198 | −0.911132 | DOWNREG IN TRAMP |
| MPO | 6.261636 | 5.35168 | −0.909956 | DOWNREG IN TRAMP |
| SPRR1A | 7.303926 | 6.450634 | −0.853292 | DOWNREG IN TRAMP |
| KLF4 | 5.972053 | 5.12466 | −0.847393 | DOWNREG IN TRAMP |
| RNU3B1 | 8.152078 | 7.359946 | −0.792132 | DOWNREG IN TRAMP |
| RNU3B3 | 8.152078 | 7.359946 | −0.792132 | DOWNREG IN TRAMP |
| RNU3B4 | 8.152078 | 7.359946 | −0.792132 | DOWNREG IN TRAMP |
| MT-ATP6 | 11.152495 | 10.3733 | −0.779195 | DOWNREG IN TRAMP |
| MT-ATP8 | 11.152495 | 10.3733 | −0.779195 | DOWNREG IN TRAMP |
| TMEM170A | 7.168522 | 6.393305 | −0.775217 | DOWNREG IN TRAMP |
| LYNX1 | 6.509217 | 5.743623 | −0.765594 | DOWNREG IN TRAMP |
| IFNL3 | 7.614195 | 6.864119 | −0.750076 | DOWNREG IN TRAMP |
| PPP1R3G | 6.619849 | 5.871467 | −0.748382 | DOWNREG IN TRAMP |
| GPR15 | 6.228328 | 5.501892 | −0.726436 | DOWNREG IN TRAMP |
| UGT2A3 | 4.911755 | 4.199168 | −0.712587 | DOWNREG IN TRAMP |
| MED13L | 6.879517 | 6.175366 | −0.704151 | DOWNREG IN TRAMP |
| DNAJC10 | 5.724132 | 5.050291 | −0.673841 | DOWNREG IN TRAMP |
| NPY | 7.177505 | 6.52748 | −0.650025 | DOWNREG IN TRAMP |
| XIST | 4.846425 | 4.21413 | −0.632295 | DOWNREG IN TRAMP |
| LST1 | 6.934321 | 6.30468 | −0.629641 | DOWNREG IN TRAMP |
| WNT9A | 6.878282 | 6.249191 | −0.629091 | DOWNREG IN TRAMP |
| LRRN3 | 5.589029 | 4.959979 | −0.62905 | DOWNREG IN TRAMP |
| GPR45 | 5.821262 | 5.199841 | −0.621421 | DOWNREG IN TRAMP |
| IFIT1 | 5.804034 | 5.18294 | −0.621094 | DOWNREG IN TRAMP |
| YWHAQ | 5.732451 | 5.121101 | −0.61135 | DOWNREG IN TRAMP |
| KIR3DL1 | 5.551242 | 4.945612 | −0.60563 | DOWNREG IN TRAMP |
| EPPIN | 6.819009 | 6.216168 | −0.602841 | DOWNREG IN TRAMP |
| CRLF1 | 6.024841 | 5.423862 | −0.600979 | DOWNREG IN TRAMP |
| MAL2 | 5.271787 | 4.675268 | −0.596519 | DOWNREG IN TRAMP |
| MAP3K15 | 5.447115 | 4.854145 | −0.59297 | DOWNREG IN TRAMP |
| H1FX | 6.468248 | 5.876241 | −0.592007 | DOWNREG IN TRAMP |
| TOX4 | 3.892922 | 4.479661 | 0.586739 | UPREG IN TRAMP |
| RPL38 | 6.60822475 | 7.19496625 | 0.5867415 | UPREG IN TRAMP |
| LSM12 | 6.117599 | 6.705587 | 0.587988 | UPREG IN TRAMP |
| RPL5 | 6.2154714 | 6.8039176 | 0.5884462 | UPREG IN TRAMP |
| HAX1 | 6.001432 | 6.590249 | 0.588817 | UPREG IN TRAMP |
| ALPI | 5.728489 | 6.318577 | 0.590088 | UPREG IN TRAMP |
| TCTE3 | 6.1099925 | 6.7001345 | 0.590142 | UPREG IN TRAMP |
| RPL7 | 6.5213525 | 7.11150425 | 0.59015175 | UPREG IN TRAMP |
| MRTO4 | 6.06266 | 6.6569265 | 0.5942665 | UPREG IN TRAMP |
| HDAC1 | 7.1222465 | 7.7184935 | 0.596247 | UPREG IN TRAMP |
| UBE2H | 5.400706 | 5.9973295 | 0.5966235 | UPREG IN TRAMP |
| KRT26 | 4.576418 | 5.173867 | 0.597449 | UPREG IN TRAMP |
| TNFSF10 | 4.968375 | 5.566245 | 0.59787 | UPREG IN TRAMP |
| DPPA2 | 5.2919825 | 5.8913585 | 0.599376 | UPREG IN TRAMP |
| PNLDC1 | 5.567492 | 6.168421 | 0.600929 | UPREG IN TRAMP |
| MRPS11 | 5.715828 | 6.317477 | 0.601649 | UPREG IN TRAMP |
| PFDN6 | 5.868045 | 6.472116 | 0.604071 | UPREG IN TRAMP |
| STOML2 | 5.471422 | 6.076051 | 0.604629 | UPREG IN TRAMP |
| VDAC1 | 4.739057 | 5.344863 | 0.605806 | UPREG IN TRAMP |
| RPS8 | 8.219871929 | 8.829568 | 0.609696071 | UPREG IN TRAMP |
| TDGF1 | 6.079579 | 6.690292 | 0.610713 | UPREG IN TRAMP |
| UBE2E2 | 5.919762 | 6.531531 | 0.611769 | UPREG IN TRAMP |
| GKAP1 | 4.673868 | 5.286005 | 0.612137 | UPREG IN TRAMP |
| RPL10A | 6.271725333 | 6.884766333 | 0.613041 | UPREG IN TRAMP |
| RPS15 | 6.904076667 | 7.518351667 | 0.614275 | UPREG IN TRAMP |
| UMOD | 5.965413 | 6.58144 | 0.616027 | UPREG IN TRAMP |
| RPL9 | 7.8632155 | 8.47986875 | 0.61665325 | UPREG IN TRAMP |
| RPL30 | 7.4728119 | 8.0894858 | 0.6166739 | UPREG IN TRAMP |
| NPNT | 5.948929 | 6.566422 | 0.617493 | UPREG IN TRAMP |
| NR1I2 | 5.126106 | 5.744132 | 0.618026 | UPREG IN TRAMP |
| KRTAP16-1 | 4.635846 | 5.256192 | 0.620346 | UPREG IN TRAMP |
| H3F3A | 6.632576333 | 7.259209167 | 0.626632833 | UPREG IN TRAMP |
| H3F3B | 6.632576333 | 7.259209167 | 0.626632833 | UPREG IN TRAMP |
| MRPL34 | 5.782111 | 6.409365 | 0.627254 | UPREG IN TRAMP |
| CSE1L | 5.137071 | 5.76598 | 0.628909 | UPREG IN TRAMP |
| ST6GALNAC1 | 6.264418 | 6.896253 | 0.631835 | UPREG IN TRAMP |
| UBE2Q2 | 4.944425 | 5.578387 | 0.633962 | UPREG IN TRAMP |
| RPS17 | 6.891415333 | 7.531757333 | 0.640342 | UPREG IN TRAMP |
| RPL35 | 7.432499 | 8.07315375 | 0.64065475 | UPREG IN TRAMP |
| GMCL1 | 4.814764 | 5.463716 | 0.648952 | UPREG IN TRAMP |
| NIP7 | 4.865122 | 5.516629 | 0.651507 | UPREG IN TRAMP |
| MSL2 | 6.330507 | 6.982406 | 0.651899 | UPREG IN TRAMP |
| EIF4A1 | 6.357854333 | 7.015451 | 0.657596667 | UPREG IN TRAMP |
| LASP1 | 6.2246 | 6.885856 | 0.661256 | UPREG IN TRAMP |
| LUZP4 | 5.420406273 | 6.082919364 | 0.662513091 | UPREG IN TRAMP |
| EIF1AD | 5.398592 | 6.061553 | 0.662961 | UPREG IN TRAMP |
| TUBB3 | 5.118307 | 5.782439 | 0.664132 | UPREG IN TRAMP |
| RPL34 | 6.812256125 | 7.48376675 | 0.671510625 | UPREG IN TRAMP |
| RPL17 | 8.6381411 | 9.3102862 | 0.6721451 | UPREG IN TRAMP |
| RPL23 | 8.6381411 | 9.3102862 | 0.6721451 | UPREG IN TRAMP |
| RPL28 | 7.3877255 | 8.060629 | 0.6729035 | UPREG IN TRAMP |
| KIR3DL2 | 4.490148 | 5.163333 | 0.673185 | UPREG IN TRAMP |
| LMO2 | 6.194375 | 6.867663 | 0.673288 | UPREG IN TRAMP |
| NA | 8.854485667 | 9.528207 | 0.673721333 | UPREG IN TRAMP |
| AOC3 | 4.851769 | 5.52668 | 0.674911 | UPREG IN TRAMP |
| H2AFZ | 5.7490965 | 6.4253375 | 0.676241 | UPREG IN TRAMP |
| RPL37 | 6.697474 | 7.3776735 | 0.6801995 | UPREG IN TRAMP |
| TMSB10 | 6.4661765 | 7.1498185 | 0.683642 | UPREG IN TRAMP |
| AMY2A | 5.5242838 | 6.2095316 | 0.6852478 | UPREG IN TRAMP |
| AMY2B | 5.5242838 | 6.2095316 | 0.6852478 | UPREG IN TRAMP |
| PPIA | 7.218713167 | 7.904503667 | 0.6857905 | UPREG IN TRAMP |
| PPIH | 7.96199975 | 8.650384 | 0.68838425 | UPREG IN TRAMP |
| BEGAIN | 5.547309 | 6.236008 | 0.688699 | UPREG IN TRAMP |
| NT5C3A | 5.18496 | 5.88516 | 0.7002 | UPREG IN TRAMP |
| RPS28 | 7.77441325 | 8.480784583 | 0.706371333 | UPREG IN TRAMP |
| RPL27 | 7.019244167 | 7.728438 | 0.709193833 | UPREG IN TRAMP |
| IL24 | 5.822699 | 6.533534 | 0.710835 | UPREG IN TRAMP |
| COPS9 | 5.550281 | 6.267586 | 0.717305 | UPREG IN TRAMP |
| NEK2 | 5.869081 | 6.58744 | 0.718359 | UPREG IN TRAMP |
| SOCS2 | 5.472304 | 6.193221 | 0.720917 | UPREG IN TRAMP |
| UBL5 | 5.35799 | 6.081819 | 0.723829 | UPREG IN TRAMP |
| UBE2D3 | 6.4919555 | 7.218215 | 0.7262595 | UPREG IN TRAMP |
| VHL | 5.126836 | 5.855295 | 0.728459 | UPREG IN TRAMP |
| RPL23A | 7.075150533 | 7.805176367 | 0.730025833 | UPREG IN TRAMP |
| AICDA | 4.75671 | 5.493925 | 0.737215 | UPREG IN TRAMP |
| LDHA | 6.949646 | 7.687545 | 0.737899 | UPREG IN TRAMP |
| CNEP1R1 | 5.093965 | 5.834359 | 0.740394 | UPREG IN TRAMP |
| RPL29 | 9.731314667 | 10.47313587 | 0.7418212 | UPREG IN TRAMP |
| SPCS1 | 6.360776 | 7.105179 | 0.744403 | UPREG IN TRAMP |
| RPL41 | 9.0427918 | 9.7879746 | 0.7451828 | UPREG IN TRAMP |
| SP110 | 7.431632667 | 8.17828 | 0.746647333 | UPREG IN TRAMP |
| PMP22 | 7.431632667 | 8.17828 | 0.746647333 | UPREG IN TRAMP |
| ARCN1 | 5.1359 | 5.882582 | 0.746682 | UPREG IN TRAMP |
| UQCRB | 5.850610667 | 6.602469667 | 0.751859 | UPREG IN TRAMP |
| SLC25A19 | 6.694142722 | 7.446046167 | 0.751903444 | UPREG IN TRAMP |
| UBE2N | 4.750683 | 5.50388 | 0.753197 | UPREG IN TRAMP |
| SNRPE | 5.56195 | 6.319007 | 0.757057 | UPREG IN TRAMP |
| ACKR1 | 5.301382 | 6.059632 | 0.75825 | UPREG IN TRAMP |
| RPL21 | 8.995938667 | 9.774761333 | 0.778822667 | UPREG IN TRAMP |
| LEFTY2 | 4.06356 | 4.843924 | 0.780364 | UPREG IN TRAMP |
| RPL31 | 6.676469667 | 7.475938333 | 0.799468667 | UPREG IN TRAMP |
| RPL35A | 7.471309667 | 8.272641333 | 0.801331667 | UPREG IN TRAMP |
| RPL7A | 8.902748222 | 9.712848259 | 0.810100037 | UPREG IN TRAMP |
| RPL39 | 5.712307 | 6.524483 | 0.812176 | UPREG IN TRAMP |
| NACA | 6.618499 | 7.4467945 | 0.8282955 | UPREG IN TRAMP |
| SP140 | 7.564562 | 8.408509 | 0.843947 | UPREG IN TRAMP |
| MRPL23 | 5.8653735 | 6.718201 | 0.8528275 | UPREG IN TRAMP |
| VDAC3 | 4.719043333 | 5.638291667 | 0.919248333 | UPREG IN TRAMP |
| VDAC1P5 | 4.719043333 | 5.638291667 | 0.919248333 | UPREG IN TRAMP |
| ATP5L | 6.3129462 | 7.2759266 | 0.9629804 | UPREG IN TRAMP |
| DIMT1 | 4.137816 | 5.183852 | 1.046036 | UPREG IN TRAMP |
| GMCL1P1 | 6.046781 | 7.0991925 | 1.0524115 | UPREG IN TRAMP |
| ARFGAP2 | 6.024623 | 7.141176 | 1.116553 | UPREG IN TRAMP |
| RPL22 | 5.681224 | 6.802828 | 1.121604 | UPREG IN TRAMP |