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. 2019 Apr 2;9:5500. doi: 10.1038/s41598-019-41933-4

Figure 1.

Figure 1

Correlations between pulmonary levels of malondialdehyde (MDA) as a surrogate of ROS formation, low COX/SDH-activity ratios as a marker of impaired mtDNA-encoded respiratory chain function, low COX2/COX4-ratios as a measure of impaired mtDNA encoded protein synthesis, and the common mtDNA deletion as a marker of mtDNA mutagenesis. Depicted are all lung biopsies.