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. 2019 Apr 2;9:5483. doi: 10.1038/s41598-019-41476-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Body and muscle weight of aged skeletal muscle-specific Dicer knockout mouse. (A) No difference was observed in the body weight (mg) of 26 month old vehicle-treated (wild-type, WT) and tamoxifen-treated (knockout, KO) mice which were treated at four months of age. (B) No difference was observed in the weight of hind limb muscles (plantaris, soleus, gastrocnemius, EDL, TA) and heart of KO and WT mice. Values are presented as the mean ± SEM (n = 8–9).