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. 2019 Apr 2;9:5484. doi: 10.1038/s41598-019-40759-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Association of Enhancer-SF expression levels with cancer-related biological programs. (A) Schematic overview of steps used to correlate Enhancer- and Suppressor-SF expression to other genes in the genome followed by over-representation and gene-set enrichment analyses. (B) Top altered pathways in over-representation analysis of the top 500 genes positively correlating with Suppressor-SFs. (C) Top altered pathways in over-representation analysis of the top 500 genes positively correlating with Enhancer-SFs. (D) Cytoscape visualization of GSEA of pathways highly correlated to Suppressor-SFs. (E) Same as in (D) but for Enhancer-SFs.