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. 2019 Apr 2;9:5498. doi: 10.1038/s41598-019-41923-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A,B) Rivermead post-concussion questionnaire (RPQ) difference in each follow-up assessment from baseline. Each point is the average change ± standard error (SE) of all short-term PCS (SPCS) participants in each subgroup: Active (n = 4) and Sham (n = 4). (A) RPQ3 are the score of the first three symptoms in RPQ. (B) RPQ13 are the score of the last 13 symptoms in RPQ. (C,D) RPQ difference in each follow-up assessment from baseline. Each point is the average change ± SE of all long-term PCS (LPCS) participants in each subgroup: Active (n = 5) and Sham (n = 5). (C) RPQ3 are the score of the first three symptoms in RPQ. (D) RPQ13 are the score of the last 13 symptoms in RPQ. (*) indicate for significant difference.