Table 1.
Patient Demographics and average ± standard deviation (SD) outcome scores: Treatment was at a frequency of 20 Hz in trains of 30 pulses with an inter-train interval of 28.5 sec at 100% of resting motor threshold. 25 pulse trains were delivered (750 pulses/day) at each of 13 treatment sessions (10 in first 2 weeks and 3 in third week). base = baseline, post = post treatment, FU = follow up (FU1 = 30 days after treatment, FU2 = 60 days after treatment). MOCA was only applied at inclusion screening. In the MADRS baseline column superscript indicates a subject was on depression related medication(s) (1Lamictal, Zeldox, Zoloft, Clonazapam, 2Trazadone, 3Amitriptyline, 4Amitriptyline).
| Groups | Age ± std | Year since injury | Sex | MOCA base | RPQ3 | RPQ13 | MADRS | EVestG AP-area | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sham | base | post | FU-1 | FU-2 | base | post | FU-1 | FU-2 | base | post | FU-1 | FU-2 | base | post | FU-1 | FU-2 | ||||
| LPCS, n = 5 | 56.8 ± 10.8 | 2.5 ± 1.2 | 3M, 2F | 27.0 ± 3.9 | 6.6 ± 3.8 | 5.6 ± 2.6 | 6.2 ± 3.6 | 5.8 ± 3.5 | 28.5 ± 12.7 | 30.6 ± 7.8 | 27.1 ± 6.5 | 28.6 ± 9.3 | 9.21,4 ± 6.6 | 6.8 ± 5.0 | 8.4 ± 5.7 | 7.8 ± 1.5 | 33.9 ± 11.3 | 33.0 ± 13.5 | 33.0 ± 11.3 | 36.5 ± 12 |
| SPCS, n = 4 | 49.3 ± 5.4 | 0.7 ± 0.2 | 1M, 3F | 27.3 ± 1.7 | 8.9 ± 3.4 | 6.8 ± 3.9 | 5.5 ± 2.8 | 4.3 ± 3.1 | 34.6 ± 5.7 | 28.4 ± 15.2 | 34.3 ± 14.4 | 29.3 ± 19.1 | 20.3 1 ± 12.9 | 18.0 ± 15.9 | 12.3 ± 12.0 | 17.0 ± 12.7 | 20.0 ± 9.3 | 28.0 ± 10.8 | 27.2 ± 16.3 | 27.8 ± 11.9 |
| All, n = 9 | 53.0 ± 8.8 | 1.6 ± 1.2 | 4M, 5F | 27.1 ± 3.0 | 7.6 ± 3.6 | 6.1 ± 3.1 | 5.9 ± 3.1 | 5.1 ± 3.2 | 31.2 ± 10.2 | 29.6 ± 10.9 | 29.8 ± 9.9 | 28.9 ± 13.5 | 14.1 ± 10.8 | 11.8 ± 11.9 | 9.9 ± 8.0 | 11.9 ± 9.2 | 27.7 ± 12.2 | 30.8 ± 11.9 | 30.8 ± 12.6 | 32.2 ± 12.0 |
| Active | ||||||||||||||||||||
| LPCS, n = 5 | 50.8 ± 17.4 | 2.8 ± 1.3 | 4M, 1F | 27.4 ± 0.9 | 5.7 ± 2.0 | 6.4 ± 2.9 | 5.8 ± 2.5 | 6.7 ± 2.0 | 24.5 ± 5.7 | 23.8 ± 9.6 | 23.6 ± 10.2 | 24.6 ± 12.3 | 12.0 2 ± 5.2 | 11.6 ± 5.5 | 15.0 ± 8.9 | 15.6 ± 12.0 | 30.7 ± 7.1 | 29.5 ± 10.1 | 28.1 ± 11.8 | 33.5 ± 11.0 |
| SPCS, n = 4 | 42.5 ± 15.4 | 0.8 ± 0.2 | 1M, 3F | 29.0 ± 0.8 | 10.3 ± 1.7 | 7.0 ± 3.4 | 5.0 ± 4.1 | 3.8 ± 3.8 | 41.5 ± 6.9 | 33.4 ± 7.6 | 16.8 ± 11.0 | 17.5 ± 10.0 | 19.0 ± 5.7 | 12.3 ± 4.0 | 6.0 ± 2.0 | 5.0 ± 1.0 | 19.8 ± 2.1 | 34.0 ± 8.4 | 34.3 ± 9.0 | 41.8 ± 8.0 |
| All, n = 9 | 46.7 ± 15.3 | 1.8 ± 1.4 | 5M, 4F | 28.1 ± 1.2 | 7.7 ± 3.0 | 6.7 ± 2.9 | 5.5 ± 2.9 | 5.6 ± 2.9 | 32.1 ± 10.7 | 28.1 ± 9.6 | 21.1 ± 10.3 | 21.9 ±11.3 | 15.1 ± 6.3 | 11.9 ± 4.6 | 11.6 ± 8.3 | 11.6 ± 10.6 | 25.9 ± 7.8 | 31.5 ± 9.1 | 30.4 ± 10.6 | 37.2 ± 10.2 |