Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 1;35(10):585–590. doi: 10.1089/dna.2015.3022

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright 2016, Mary Ann Liebert, Inc.

PMC Copyright notice

FIG. 1. — Disruption of Gen1 and Eme1 caused synthetic lethality. RT-PCR showed disrupted expression of Gen1 (A) and Eme1 (B) in MEFs bearing homozygous mutations, respectively. Genotyping PCR of neonates (C, D) and embryonic day 8.5 (E8.5) offspring (D), and E3.5 blastocysts (D) from indicated mice inbreeding detected no double homozygous mutant (Gen1^PB/PB; Eme1^PB/PB), respectively. p-Value of Fisher's exact test was labeled in the figure. MEFs, mouse embryonic fibroblasts; PB, piggyBac; RT-PCR, reverse transcription polymerase chain reaction; WT, wild-type.