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. 2019 Mar 28;12:2365–2372. doi: 10.2147/OTT.S192111

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© 2019 Zong et al. This work is published and licensed by Dove Medical Press Limited

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Pathology revealed that the metastatic tumor of the liver surface was SMs (sarcoma) derived from YST.

Notes: (A) Variably sized tumor cells with severe nuclear atypia and edematous stroma with multifocal hemorrhage (H&E, 100×); (B) scattered pleomorphic tumor giant cells (H&E, 400×); (C) focal positivity for AE1/AE3 immunostaining in tumor cells; AE1/AE3 immunostaining was positive in YSTs and some sarcomatous tumors (IHC staining, 200×); (D, E) immunonegativity for GPC3 and SALL4 in tumor cells; (F) Ki-67-positive expression found in approximately 10% of tumor cells (IHC staining, 400×).

Abbreviations: IHC, immunohistochemistry; SMs, somatic-type malignancies; YST, yolk sac tumor.