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. 2019 Mar 20;10:254. doi: 10.3389/fphar.2019.00254

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Copyright © 2019 Dang, Li, Sun, Wang, Lin, Zhang, Dai and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolite and pathway analysis of drug-induced perturbations. (A) Numbers of drug-intervened metabolites in ALI; (B) numbers of drug-intervened pathways in ALI. The summarization of drug-intervened global, local and symbiotic pathways is presented in the center. BS: decoctions of B. chinense-S. baicalensis; SC: decoctions of S. baicalensis; BU: decoctions of B. chinense; BA: water solution of baicalin; SA: water solution of saikosaponin; MI: the mixture of baicalin and saikosaponin.