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. 2019 Mar 28;12:2383–2396. doi: 10.2147/OTT.S191158

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© 2019 You et al. This work is published and licensed by Dove Medical Press Limited

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Luteolin inhibited cell proliferation in glioma cells.

Notes: (A) The molecular structural formula of luteolin. (B) LN229 cells were incubated with different concentrations of luteolin for 24 and 48 hours, and then the cell viability was measured by CCK-8 assay. (C) U251 cells were incubated with different concentrations of luteolin for 24 and 48 hours, and then the cell viability was measured by CCK-8 assay. (D) HEB cells were incubated with different concentrations of luteolin for 24 and 48 hours, and then the cell viability was measured by CCK-8 assay. (E) LN229, U251, and HEB cell lines were incubated with luteolin and temozolomide, respectively, for 24 hours. Data are expressed as the mean ± SD of three independent experiments (^**P<0.01, ^***P<0.001 vs the control group; n=3).

Abbreviations: CCK-8, Cell Counting Kit-8; TMZ, temozolomide.