Skip to main content
. Author manuscript; available in PMC: 2019 Apr 2.
Published in final edited form as: JCO Precis Oncol. 2018 Mar 29;2:1–12. doi: 10.1200/PO.17.00191

Figure 2.

Figure 2

(A) T1-weighted MR image of a metastatic GIST to the liver (arrow) from case 5. (B) SDHB immunonegativity on SDHB immunohistochemistry performed on the wt GIST tumour from the same patient. (C) Axial fused 18F-FDG PET/CT image demonstrating an FDG-avid carotid body PGL after SDH deficiency was demonstrated on 1H-MRS. (D-E) Spectra acquired at 1H-MRS from the same case before and during treatment with a multi-kinase inhibitor. (F-G) Axial fused 18F-FDG PET/CT images and corresponding coronal PET projections illustrating the increase in disease burden and FDG avidity over time (SUV: 15.1 and 27.1) which correlates with the increase in the succinate peak demonstrated on 1H-MRS.