Table 2.
Characteristics of the Infants Who Survived to Discharge Based on the Number of Mechanical Ventilation Coursesa
| No. of Mechanical Ventilation Courses | ||||
|---|---|---|---|---|
| Characteristic | 1 (n = 921) | 2 (n = 636) | 3 (n = 502) | ≥4 (n = 808) |
| Demographics | ||||
| Gestational age, median (IQR), wk | 27.0 (25.9–28.1) | 26.0 (25.0–27.1) | 25.7 (24.9–26.9) | 25.1 (24.3–26.3) |
| Birth weight, median (IQR), g | 848 (737–930) | 800 (685–890) | 750 (650–890) | 710 (614–815) |
| Male | 393 (42.7) | 309 (48.6) | 246 (49.0) | 441 (54.6) |
| SGA | 297 (32.3) | 148 (23.3) | 114 (22.7) | 198 (24.5) |
| 5-Minute Apgar score, median (IQR) | 8 (6–8) | 7 (6–8) | 7 (6–8) | 7 (6–8) |
| Treatments and morbidities | ||||
| Surfactant | 624 (67.8) | 471 (74.1) | 406 (80.9) | 638 (79.0) |
| PDA treatment | 376 (40.8) | 346 (54.4) | 313 (62.4) | 577 (71.4) |
| NEC | 23 (2.5) | 33 (5.2) | 39 (7.8) | 115 (14.2) |
| Bacterial sepsis | 217 (23.6) | 242 (38.1) | 245 (48.8) | 507 (62.8) |
| Postnatal dexamethasone treatment | 74 (8.0) | 122 (19.2) | 142 (28.3) | 380 (47.0) |
| Mechanical ventilation duration, median (IQR), d | 4 (2–13) | 19 (9–37) | 36 (19–55) | 59 (41–87) |
| Mechanical ventilation courses, median (IQR), No. | KD | 2 (2) | 3 (3) | 5 (4–6) |
Abbreviations: BPD, bronchopulmonary dysplasia; IQR, interquartile range; NEC, necrotizing enterocolitis; PDA, patent ductus arteriosus; SGA, small for gestational age.
a
Data are presented as number (percentage) of patients unless otherwise indicated. Differences between categories for all patient characteristics are statistically significant at P < .001.