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. Author manuscript; available in PMC: 2019 Apr 2.
Published in final edited form as: JAMA Pediatr. 2015 Nov;169(11):1011–1017. doi: 10.1001/jamapediatrics.2015.2401

Table 3.

Rates of Death and the Study Outcomes Determined for Survivors Based on the Cumulative Duration of Mechanical Ventilation and the Number of Mechanical Ventilation Courses

No. (%) of Patients
Variable BPD Discharged on Oxygen Tracheostomy Deatha
Duration of mechanical ventilation, d
 ≤7 (n = 759) 202 (26.6) 102 (13.4) 1 (0.1) 177 (18.9)
 8–21 (n = 562) 287 (51.1) 109 (19.4) 1 (0.2) 116 (17.1)
 22–35 (n = 382) 248 (64.9) 115 (30.1) 2 (0.5) 60 (13.6)
 ≥36 (n = 1164) 957 (82.2) 530 (45.5) 27 (2.3) 123 (9.6)
P value <.001 <.001 <.001 <.001
No. of mechanical ventilation courses
 1 (n = 921) 335 (36.4) 165 (17.9) 2 (0.2) 162 (15.0)
 2 (n = 636) 360 (56.5) 183 (28.8) 7 (1.1) 93 (12.8)
 3 (n = 502) 345 (68.7) 178 (35.5) 3 (0.6) 71 (12.4)
 ≥4 (n = 808) 654 (80.9) 330 (40.8) 19 (2.4) 150 (15.7)
P value <.001 <.001 <.001 .18
a

Numbers of deaths determined for the full cohort are as follows: 936, 678, 442, and 1287 for the 7 days or less, 8 through 21 days, 22 through 35 days, and 36 days or more of mechanical ventilation, respectively, and 1083, 729, 573, and 958 for 1, 2, 3, and 4 or more courses of mechanical ventilation, respectively.