Table 4.
Associations between timing of occupation and amyotrophic lateral sclerosis diagnosis in men
| Agriculture, hunting, forestry, fishing | Construction | |||||
|---|---|---|---|---|---|---|
| Cases n (%) | Controls n (%) | OR (95% CI) | Cases n (%) | Controls n (%) | OR (95% CI) | |
| Longest job* | 33 (3.06%) | 2800 (2.59%) | 1.14 (0.80 to 1.63) | 69 (6.39%) | 5945 (5.51%) | 1.17 (0.92 to 1.51) |
| Years before diagnosis†‡ | ||||||
| 0years before | 181 (16.77%) | 16 072 (14.90%) | 1.21 (1.01 to 1.44) | 396 (36.70%) | 37 256 (34.53%) | 1.21 (1.05 to 1.38) |
| 5years before | 175 (16.22%) | 15 539 (14.40%) | 1.20 (1.01 to 1.44) | 389 (36.05%) | 36 121 (33.48%) | 1.23 (1.07 to 1.41) |
| 10years before | 170 (15.76%) | 14 826 (13.74%) | 1.21 (1.01 to 1.45) | 375 (34.75%) | 34 454 (31.93%) | 1.25 (1.09 to 1.44) |
| Number of years in the job‡ | ||||||
| None | 901 (83.50%) | 92 127 (85.38%) | Reference | 687 (63.67%) | 71 278 (66.06%) | Reference |
| <1 year | 120 (11.12%) | 9964 (9.23%) | 1.28 (1.04 to 1.58) | 230 (21.32%) | 20 363 (18.87%) | 1.25 (1.06 to 1.47) |
| 1–4years | 45 (4.17%) | 3676 (3.41%) | 1.36 (0.99 to 1.87) | 93 (8.62%) | 9053 (8.39%) | 1.18 (0.94 to 1.49) |
| ≥5 years | 13 (1.20%) | 2133 (1.98%) | 0.64 (0.36 to 1.14) | 69 (6.39%) | 7206 (6.68%) | 1.13 (0.87 to 1.46) |
| Age at first employment‡ | ||||||
| None | 901 (83.50%) | 92 127 (85.38%) | Reference | 687 (63.67%) | 71 278 (66.06%) | Reference |
| ≤20years | 51 (4.73%) | 4609 (4.27%) | 1.18 (0.85 to 1.64) | 63 (5.84%) | 5988 (5.55%) | 1.27 (0.95 to 1.68) |
| 21–30 years | 84 (7.78%) | 7453 (6.91%) | 1.22 (0.96 to 1.54) | 218 (20.20%) | 20 402 (18.91%) | 1.22 (1.03 to 1.45) |
| 31–40 years | 25 (2.32%) | 2138 (1.98%) | 1.24 (0.81 to 1.89) | 65 (6.02%) | 6110 (5.66%) | 1.12 (0.85 to 1.48) |
| ≥41 years | 18 (1.67%) | 1573 (1.46%) | 1.23 (0.75 to 2.00) | 46 (4.26%) | 4122 (3.82%) | 1.21 (0.89 to 1.67) |
| Calendar year of first employment‡ | ||||||
| None | 901 (83.50%) | 92 127 (85.38%) | Reference | 687 (63.67%) | 71 278 (66.06%) | Reference |
| ≤1964 | 11 (1.02%) | 1228 (1.14%) | 0.94 (0.51 to 1.72) | 16 (1.48%) | 1673 (1.55%) | 1.07 (0.64 to 1.77) |
| 1965–1974 | 75 (6.95%) | 6454 (5.98%) | 1.23 (0.96 to 1.57) | 188 (17.42%) | 15 479 (14.35%) | 1.35 (1.13 to 1.61) |
| 1975–1984 | 56 (5.19%) | 4544 (4.21%) | 1.32 (0.98 to 1.78) | 98 (9.08%) | 10 205 (9.46%) | 1.05 (0.83 to 1.32) |
| ≥1985 | 33 (3.06%) | 3313 (3.07%) | 1.13 (0.76 to 1.67) | 90 (8.34%) | 9265 (8.59%) | 1.15 (0.90 to 1.49) |
*
Models adjusted for socioeconomic status, residential location, marital status and duration.
†
Models are separate for each lagged exposure. Percentages presented are for the distribution of subjects with exposure in each case or control group.
‡
All models adjusted for socioeconomic status, residential location and marital status.