. Author manuscript; available in PMC: 2020 Mar 15.

Published in final edited form as: Life Sci. 2019 Feb 5;221:212–223. doi: 10.1016/j.lfs.2019.01.040

Table 3.

Comparisons of Metabolites from Heart and Serum of MI and Sham MI Rabbits.^a

		Source:	Left Ventricle Free Wall			Intraventricular Septum			Right Ventricle			Serum
Network			MI/Sham	Raw data	Log data	MI/Sham	Raw data	Log data	MI/Sham	Raw data	Log data	MI/Sham	Raw data	Log data
Regions	Metabolite	KEGG	Mean	p value	p value	Mean	p value	p value	Mean	p value	p value	Mean	p value	p value
Amines	Ethanolamine	C00189				0.771	0.059	0.038
	Phosphoethanolamine	C00346	0.767	0.083	0.043
Amino Acids	Aspartic acid	C00049	1.875	0.046	0.070
	Aminomalonate	C00872	0.719	0.001	0.001
	Beta-alanine	C00099				0.557	0.013	0.014				0.589	0.023	0.014
	Glutathione	C00051				1.768	0.003	0.003
	Methionine	C00073							1.220	0.012	0.016
	Ta uri ne	C00245	3.499	0.001	0.007	1.899	0.001	0.000	3.156	0.036	0.083
Aromatics	Benzoic Acid	C00180				0.765	0.009	0.004
	Nicotinamide	C00153				0.682	0.004	0.027
	Phenylalanine	C00079	1.445	0.047	0.075	1.582	0.040	0.048
Fatty Acids	Linolenic acid	C06427	1.334	0.056	0.046
	Palmitoleic	C08362				0.674	0.017	0.013
	Stearic acid	C01530										1.262	0.048	0.075
Organic Acids	Dehydroascorbic acid	C05422				1.803	0.006	0.009				1.197	0.005	0.005
& TCA Cycle	Malic acid	C00711										0.539	0.060	0.039
	Succinic acid	C00042				0.706	0.049	0.025	0.645	0.026	0.014
	Threonic acid	C01620							1.514	0.038	0.059	1.809	0.007	0.038
	2-hydroxyvaleric acid	na							0.662	0.040	0.043
Phosphates	Phosphate	C00009										0.605	0.100	0.039
	Methanophosphate	na	1.970	0.017	0.082
	Sulfuric acid(Sulfate)	C00059	2.143	0.020	0.035
Purines	Hypoxanthine	C00262							1.537	0.041	0.040
	Inosine	C00294	1.439	0.011	0.031	1.358	0.011	0.023	1.719	0.025	0.025
Sterols	Cholesterol	C00187							1.199	0.025	0.033
Sugars	Conduritol-beta-epoxide	na				0.673	0.050	0.079
Alcohol	Glycerol	C00116				0.621	0.020	0.014
	Isothreitol	C16884										1.996	0.040	0.089
	Myo-inositol	C00137	0.787	0.012	0.011	0.870	0.078	0.064	0.864	0.127	0.094	1.541	0.056	0.066
Urea	Hydroxycarbamate NIST	na				0.761	0.024	0.020
	Urea	C00086	0.835	0.032	0.028

KEGG = Compound identifier in the KEGG resource database; MI/Sham = ratio of the mean signal in MI and Sham rabbits; Raw data and Log2 data p values represent comparisons of MI and Sham rabbit signal values using Welch’s t-test.