Table 2. Odds ratios of lung cancer occurrence in relation to serum folate, RBC folate and homocysteine levels, in study population from northern Poland, calculated by conditional logistic regression with adjustment for sex, age and pack-years of smoking.
| Variable | Lung cancer cases (%) | Controls (%) | OR (95% CI), P | |
|---|---|---|---|---|
| Serum folates nmol/l |
≤17.5 | 52 (39.4) | 200 (50.5) | 1 (Ref) |
| >17.5 | 80 (60.6) | 196 (49.5) | 1.54 (1.04–2.29), P = 0.031 | |
| RBC folates nmol/l |
≤506.5 | 37 (39.8) | 140 (50.2) | 1 (Ref) |
| >506.5 | 56 (60.2) | 139 (49.8) | 1.53 (0.95–2.47), P = 0.084 | |
| RBC folates corrected nmol/l |
≤474.8 | 37 (39.8) | 139 (50.0) | 1 (Ref) |
| >474.8 | 56 (60.2) | 139 (50.0) | 1.51 (0.93–2.43), P = 0.0934 | |
| Homocysteine μmol/l |
≤ 14.7 | 56 (43.4) | 203 (51.4) | 1 (Ref) |
| >14.7 | 73 (56.6) | 192 (48.6) | 1.41 (0.93–2.14), P = 0.1021* |
*homocysteine measures for 3 cases were not available, thus 9 matched subjects from the control group were excluded from analyses as uninformative data