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. 2019 Apr 2;14(4):e0214476. doi: 10.1371/journal.pone.0214476

Fig 4. Measurement of endothelial function in isolated aortic segments of ApoE−/− mice upon NaSCN treatment in organ chamber experiments.

Fig 4

(A) Definition of the maximal endothelial contraction by incubation with increasing phenylephrine concentrations. (B) Assessment of endothelium-independent vasodilation as a percentage of the maximal contraction with increasing concentrations of nitroglycerin. (C) Assessment of endothelium-dependent vasodilation as a percentage of the maximal contraction with increasing concentrations of carbachol. Data are presented as the mean ± SEM, n = 4–5, **p ≤ 0.01, ***p ≤ 0.005 vs. vehicle.