Table 4.
Impact of treatment time, (R)‐ and (S)‐citalopram on MMSE
| Time model | Time and (R)‐model | Time and (S)‐model | Time, (R)‐ and, (S)‐combination model | |||||
|---|---|---|---|---|---|---|---|---|
| Time | Time | R | Time | S | Time | R | S | |
| Maximum contribution | 1.04 | 1.40 | −9.38 | 1.43 | −2.07 | 1.43 | −1.09 | −0.18 |
| Minimum contribution | 0.06 | 0.10 | −0.16 | 0.09 | −0.23 | 0.09 | −0.19 | −0.03 |
| Mean | 0.37 | 0.51 | −0.91 | 0.52 | −0.61 | 0.52 | −0.51 | −0.07 |
| Median | 0.30 | 0.42 | −0.48 | 0.42 | −0.57 | 0.42 | −0.47 | −0.06 |
| SD | 0.22 | 0.30 | 1.30 | 0.31 | 0.30 | 0.31 | 0.18 | 0.03 |
| nonmem objective | 2033.00 | 2026.00 | 2028.00 | 2028.57 | ||||