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. 2019 Apr 2;2019(4):CD011118. doi: 10.1002/14651858.CD011118.pub3

Connelly 2006.

Methods RCT. 2 arms. Assessed at pretreatment, post‐treatment, 2 months, 3 months
Participants End of treatment: N = 36
 Start of treatment: N = 37
 Sex: 18 F, 19 M
 Mean age: 10.0 (range 7‐12)
Source: clinic
 Diagnosis: headache
 Mean years of pain: not given
Interventions "CD‐ROM behavioural”
 "Wait‐list neurology TAU"
Outcomes Primary pain outcome: clinical reduction in headache frequency
 Primary disability outcome: Ped‐MIDAS
Primary depression outcome: none
Primary anxiety outcome: none
Primary satisfaction outcome: none
Measures reported:
total pain (headache diary)
 Pediatric Migraine Disability Assessment (Ped‐MIDAS)
Notes Funding source: educational grant from AstraZeneca LP
Declarations of interest: none stated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "Randomly assigned to one of two groups by a research assistant using a uniform random numbers table."
 Comment: probably done
Allocation concealment (selection bias) Low risk "Randomly assigned to one of two groups by a research assistant using a uniform random numbers table."
 Comment: probably done
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk "Study neurologists remained blind to randomisation condition throughout the study. Chances of unbinding were limited because follow‐up appointments with the study neurologist were scheduled for 2 months following the initial assessment."
 Comment: probably done
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Measures completed at home and mailed back
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Attrition is described, however significant descriptions between completers and non‐completers were not reported
Selective reporting (reporting bias) Low risk Data were fully reported