Table 4. Comparison of Epx and ACh binding site metrics (α−γ).
Structural metrics | ACh | Epx | ||
---|---|---|---|---|
AR | AR* | AR | AR* | |
dx (Å) | 3.5 | 1.7 | 4.9 | 3.1 |
d93 | 6.4 | 6.1 | 8.1 | 4.9 |
d149 | 6.6 | 5.0 | 7 | 5.0 |
d190 | 5.6 | 7.0 | 7.7 | 6.4 |
d198 | 5.3 | 5.0 | 8.8 | 6.6 |
d55 | 7.7 | 5.5 | 5.7 | 5.1 |
dloopC | 17.1 | 19.9 | 13.6 | 15.3 |
volume (Å3) | 84.2 | 47.4 | 116.3 | 91.4 |
Θs (degrees) | 5.4 | 2.4 | 5.7 | 2.3 |
Θa | 125.2 | 292.7 | 45.6 | 321.5 |