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. 2019 Mar 12;151(4):532–554. doi: 10.1085/jgp.201812294

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© 2019 Zawieja et al.

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Figure 9. — Sharp electrode LMC membrane potential recordings in pressurized IALV from Ano1fl/fl and SMMHC-CreER^T2-Ano1KO mice. Representative 10-s membrane potential recording made with sharp electrode impalements of an LMCs from pressurized IALVs isolated from an Ano1fl/fl control mouse (A) or SMMHC-CreER^T2-Ano1KO mouse (B). The recorded action potentials were analyzed to assess action potential frequency (C), resting membrane potential (D), the linear diastolic depolarization rate (E), the action potential initiation threshold potential (F), the steepness of the action potential upstroke (G), peak voltage achieved during the action potential (H), the plateau voltage (I), and plateau duration (J). *, P < 0.05 comparing SMMHC-CreER^T2-Ano1KO (n = 8) versus Ano1fl/fl (n = 11).