Table 2:
Sociodemographic Features
| Depressed at Baseline (n = 43) |
Never depressed at Baseline (n = 72) |
Remitted Depression at Baseline (n = 22) |
Significance | |
|---|---|---|---|---|
| Age (yrs), mean (sd) | 67.9 (9.8) | 68.6 (10.4) | 68.1 (10.5) | p = 0.924 |
| Gender | 19 M, 24 F | 51 M, 21 F | 10 M, 12 F | p = 0.008 |
| Education (yrs), mean (sd) | 15.2 (2.3) | 16.9 (3.4) | 15.9 (2.8) | p = 0.017 |
| MMSE, mean (sd) (range 0-30)* | 25.4 (5.5) | 26.8 (3.1) | 27.2 (2.7) | p = 0.130 |
| Parkinson Features | ||||
| Age symptom onset, mean (sd) | 56.9 (12.0) | 58.6 (11.2) | 59.0 (12.4) | p = 0.692 |
| Symptom duration (yrs), mean (sd) | 11.0 (7.8) | 10.0 (6.3) | 9.1 (5.2) | p = 0.529 |
| Presence of motor fluctuations (% n) ** | 70.7% | 54.3% | 50.0% | p = 0.158 |
| Presence of early morning dystonia (% n)** | 34.1% | 27.1% | 36.4% | p = 0.615 |
| Presence of other psychiatric disorders (% n) | 53.5% | 52.8% | 68.2% | p = 0.423 |
| Use of antidepressant medication *** | 62.8% | 23.9% | 54.5% | p = 0.000 |
| Total L-dopa equivalents, mean (sd) | 787.6 (566.7) | 718.8 (438.3) | 622.2 (419.2) | p = 0.418 |
| Dopamine agonist use (% n) | 32.6% | 50.0% | 50.0% | p = 0.163 |
| Disability Severity | ||||
| Northwestern Disability Scale score, mean (sd)**** | 33.6 (11.3) | 38.5 (8.6) | 39.8 (5.9) | p = 0.010 |
| UPDRS part III, motor sub-score, mean (sd)*** | 38.9 (20.3) | 29.7 (15.9) | 22.2 (10.7) | p = 0.001 |
| Hoehn and Yahr Stage* | I 1, II 20, III 7, IV 6, V 6 | I 4, II 52, III 11, IV 2, V 3 | I 2, II 14, III 5, IV 1, V 0 | p =0.044 |
*
n=134
**
n=133
***
n=136
****
n=135