Table 1.
Study | Task used | Finding |
No. of Participants Mean Age |
Mean Disease Duration (years) |
PD and Dementia Diagnostic Criteria |
Major Clinical Assessment Tools |
|
---|---|---|---|---|---|---|---|
Recollection | Familiarity | ||||||
Davidson et al., 2006 | Yes-no recognition memory test and remember-know-new judgement |
No significant impairmentin PD |
Impaired in PD |
19 PD 66.56 (experiment1), 16 PD 67.05 (experiment 2) |
5.79 6.13 |
Criteria for PD diagnosis not specified |
MMSE MHV |
Edelstyn et al., 2007 | Yes-no recognition memory test and remember-know judgement |
Impaired in PD |
Unimpaired in PD |
17 PD 65.4 |
8.6 | Criteria for PD diagnosis not specified |
MMSE NART WAIS WR |
Cohn et al.,2010 | Noun-noun pairs recognition memory test, deep and shallow encoded |
Impaired at deep encoding in PD |
Impaired at shallow encoding in PD |
11 PD 67 |
6.4 | Criteria for PD diagnosis not specified |
MMSE |
Algarabel et al., 2010 | Yes-no recognition memory test |
Impaired in PDD and Advanced PD |
Impaired only in PDD |
20 Early PD 72.55 19 Advanced PD 75.58 10 PD Dementia 80.00 |
3.22 10.95 6.72 |
-PD diagnosis: UK Brain Bank Criteria -Dementia diagnosis based on DSM-IV criteria |
MMSE BNT WMS TMT-A |
Weiermann et al., 2010 | Yes-no recognition memory for high and low frequency words; remember-know judgement |
Unimpaired for high frequency words in PD |
Poorer sensitivity index d’ for familiarity in PD |
14 PD 63.2 |
9.43 | Criteria for PD diagnosis not specified |
MMSE Verbal Intelligence (NART) |
Rodriguez et al., 2014 | Word pairs recognition memory test, 2-alternative- forced-choice test |
Impaired in PD |
Unimpaired in PD |
20 PD 71.45 |
5.32 | - PD diagnosis: UK Brain Bank Criteria -Dementia diagnosis based on MDS criteria (Emre et al., 2007) - Dementia was exclusion criteria |
MMSE |
Cohn et al., 2016† | Associative Reinstatement Memory Task: fMRI study |
Impaired with decreased hippocampa l activation |
Unimpaired in PD |
6 PD-noMCI 9 multidomain PD-MCI 59.1 |
6.20 | -PD diagnosis: UK Brain Bank Criteria -MCI diagnosis based on MDS level 2 criteria (Litvan et al., 2012) |
MoCA Color TMT- A and B WAIS HVLT-R Category Fluency- Animals |
Pitarque et al., 2017 | Face-scene picture pairs recognition memory test |
Impaired in PD |
Unimpaired in PD |
32 non- demented PD 69.63 |
Not available |
- PD diagnosis: UK Brain Bank Criteria -Criteria for Dementia diagnosis not specified -Dementia was exclusion criteria |
MMSE WAIS Vocabulary |
Abbreviations: PDD: PD Dementia, MMSE: Mini-Mental State Examination, NART: The National Adult Reading Test, MHV: Mill Hill Vocabulary, WAIS: Wechsler Abbreviated Intelligence Scales, WR: Warrington Recognition, BNT: Boston Naming Test, WMS: Wechsler Memory Scale, TMT: Trail Making Test, MoCA: Montreal Cognitive Assessment, HVLT-R: Hopkins Verbal Learning Test-Revised MDS: Movement Disorders
All studies use behavioral methods except Cohn et al., 2016, which is an fMRI study.