Table 2.
White blood cell counts & glucose concentrations in amniotic fluid and the placental histopathology of the study population
| Without intra-amniotic inflammation or infection (n=16) |
With MIAC but without intra-amniotic inflammation (n=5) |
Sterile intra- amniotic inflammation (n=15) |
Intra- amniotic infection (n=40) |
p- value |
|
|---|---|---|---|---|---|
| White blood cell count (cells/mm3)a | 2 (0-5.5)c | 2 (0-3) | 5 (1-27.5) | 560 (57.5-1373.8) | <0.001 |
| Amniotic fluid glucose (mg/dL)a | 9 (5.8-17) | 10 (9-12) | 9 (8-11.5) | 5 (1-9) | 0.001 |
| Acute maternal inflammatory response | |||||
| Stage 1 (acute subchorionitis)b | 21.4 (3/14)d | 40 (2/5) | 42.9 (6/14)c | 26.3 (10/38)d | 0.6 |
| Stage 2 (acute chorioamnionitis)b | 14.3 (2/14)d | 0 (0/5) | 14.3 (2/14)c | 47.4 (18/38)d | 0.01 |
| Stage 3 (acute necrotizing chorioamnionitis)b | 0 (0/14)d | 0 (0/5) | 0 (0/14)c | 13.2 (5/38)d | 0.3 |
| Acute fetal inflammatory response | |||||
| Stage 1 (acute phlebitis/chorionic vasculitis)b | 21.4 (3/14)d | 40 (2/5) | 28.6 (4/14)c | 34.2 (13/38)d | 0.5 |
| Stage 2 (acute arteritis)b | 7.1 (1/14)d | 0 (0/5) | 0 (0/14)c | 23.7 (9/38)d | 0.1 |
| Stage 3 (necrotizing funisitis)b | 0 (0/14)d | 0 (0/5) | 0 (0/14)c | 7.9 (3/38)d | 0.6 |
Data are given as median (interquartile range) and percentage (number/Number)
a
Kruskal-Wallis test.
b
Fisher’s exact test.
c
One missing data
d
Two missing data
MIAC, microbial invasion of the amniotic cavity.