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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2018 Nov 14;25(3):451–458. doi: 10.1016/j.bbmt.2018.11.007

Table 4.

Optimal combination of B cell subsets diagnostic of cGvHD onset regardless of steroid use

Cell Variable Phenotyping Multivariate ROC AUC
Increased cGvHD associated CD21low* %CD27CD10+ of CD21lowCD19+ 0.87
CD27CD10CD21lowCD19+ (cells/uL)
Decreased transitional* % CD24hiCD38hi of CD19+
CD24hiCD38hiCD19+ (cells/uL)
Naïve %CD27IgD+ of CD19+
Marginal-zone like %CD27+IgD+ of CD19+
*

only combining these two populations gives a ROC AUC of 0.78