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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Clin Cancer Res. 2018 Oct 23;25(7):2136–2143. doi: 10.1158/1078-0432.CCR-18-2684

Figure 5:

Figure 5:

Shear modulus overlaid on sonograms for the representative (a) AsPC-1 and (b) BxPC-3 tumors. (c) and (d) color-segmented hyaluronic acid distributions for the corresponding (c) AsPC-1 and (d) BxPC-3 tumors. Box #1 1 had an HA density of 15.6% with a shear modulus of 298.525 kPa; Box #2 had an HA density of 7.3% and shear modulus of 139 kPa. For the AsPC-1 tumor in (b) and (d), box #1 had an HA density of 9.8% with a shear modulus of 162 kPa; box #2 had an HA density of 3.6% and shear modulus of 69 kPa. (e) shows a scatter plot of global estimate of shear modulus and HA density calculated from whole tumor slice. (f) show a local analysis of shear modulus and HA distribution shown in (c) and (d).