Fig. 2.

CVID-related clinical conditions (panel a) and mean number of co-morbidities (panel b) observed in CVID grouped according to their IgRT during the observational time. p values by the t test. **p ≤ 0.01. Abbreviation: CVID, common variable immunodeficiency; COPD, chronic obstructive pulmonary diseases; IVIG, intravenously-administered immunoglobulins; SCIG, subcutaneous Immunoglobulins; fSCIG, facilitated subcutaneous immunoglobulin; IVIG + SCIG, immunoglobulin replacement therapy by combined intravenous and subcutaneous route of administration