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. 2018 Dec 17;79(1):85–91. doi: 10.1007/s40265-018-1036-x

Features and properties of revefenacin

Alternative names 1160724; GSK 1160724; TD-4028; YUPELRI
Class Antiasthmatics; biphenyl compounds; bronchodilators; carbamates; piperidines
Mechanism of action Muscarinic receptor antagonist
Route of administration Inhalation
Pharmacodynamics Inhibits muscarinic receptor M3 in the airway smooth muscle, leading to bronchodilation
Pharmacokinetics (after inhaled administration) Time to Cmax 14–41 min; elimination half-life 22–70 h
Most frequent adverse events Cough, headache, upper respiratory tract infection, nasopharyngitis and back pain
ATC codes
 WHO ATC code R03B-B (Anticholinergics)
 EphMRA ATC code R3G3 (Anticholinergics-plain, inhalant)
Chemical name [1-[2-[[4-[(4-carbamoylpiperidin-1-yl)methyl]benzoyl]-methylamino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate