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. 2018 Dec 17;79(1):85–91. doi: 10.1007/s40265-018-1036-x

Key clinical trials of revefenacin, sponsored by Theravance Biopharma

Drug(s) Indication Phase Status Location(s) Identifier
Revefenacin, placebo Adults (aged > 40 years) with moderate to very severe COPD III Completed USA NCT02459080
Revefenacin, placebo Adults (aged > 40 years) with moderate to very severe COPD III Completed USA NCT02512510
Revefenacin, tiotropium Adults (aged > 40 years) with moderate to very severe COPD III Completed USA NCT02518139
Revefenacin, tiotropium Adults (aged > 40 years) with moderate to very severe COPD and a low PIFR (< 60 L/min) IIIb Completed USA NCT03095456
Revefenacin, formoterol, placebo Adults (aged > 40 years) with moderate to very severe COPD IIIb Completed USA NCT03573817
Revefenacin, placebo Adults (aged 40–75 years) with moderate to severe COPD II Completed USA NCT02040792
Revefenacin, ipratropium, placebo Adults (aged 40–75 years) with moderate to severe COPD II Completed New Zealand, South Africa NCT03064113; ANZCTR
U1111-1120-8290
Revefenacin, placebo Adults (aged 40–75 years) with moderate to severe COPD II Completed United Kingdom, Northern Ireland and New Zealand NCT01704404

COPD chronic obstructive pulmonary disease, PIFR peak inspiratory flow rate