Table 1.

Sputum and serum exposures of ALIS

Sputum concentrations at 1–4 h post inhalation after dosing for:
1 month	1720 μg/g
3 months	884 μg/g
6 months	1300 μg/g
Mean serum exposure after 3 months
Cmax	2.8 μg/mL (range, 1.0–4.4 μg/mL)
AUC24	23.5 μg·h/mL (range, 8.0–46.5 μg·h/mL)

The table shows sputum and serum amikacin exposures with once-daily inhalation of ALIS (590 mg) in Mycobacterium avium complex lung disease patients [14]

ALIS amikacin liposome inhalation suspension, AUC₂₄ area under the concentration-time curve from 0 to 24 h, C_max maximum concentration