Table 2.

Summary of risk of bias analysis for individual studies

Domain	Chu et al. [60]	McCauley et al. [61]	Takagaki et al. [62]	Weersing et al. [63]
Random sequence generation	+	+	+	+
Allocation concealment	?	+	+	+
Blinding participants and personnel	–	–	–	–
Blinding outcome assessment	+	+	+	+
Incomplete outcome data	+	+	+	+
Selective reporting	?	?	?	+
Other sources of bias	+	+	+	+

Key: “+” low risk of bias, “- “high risk of bias, “?” unknown/unreported