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. 2019 Mar 27;10:294. doi: 10.3389/fneur.2019.00294

Table 4.

Univariate analysis: composite outcome and associated factors among patients with DWI-neg TIA and DWI-pos TIA.

Negative outcome event N = 143 Positive outcome event N = 19 P-Value
Demographic Information
   Gender (% of males) 72 (50.3%) 12 (63.2%) 0.336
   Age, mean ± SD 73.1 ± 12.8 80.4 ± 8.5 0.017*
Past medical history
   Diabetes mellitus 45 (31.5%) 9 (47.4%) 0.198
   Hypertension 120 (83.9%) 19 (100%) 0.078
   Atrial fibrillation, PAF, flutter 25 (20.3%) 5 (26.3%) 0.553
   Hyperlipidemia 126 (88.1%) 18 (94.7%) 0.698
   Previous history of stroke 36 (25.2%) 8 (41.2%) 0.167
   Previous history of TIA 36 (25.2%) 5 (26.3%) 0.999
   Peripheral vascular disease 19 (13.3%) 6 (31.6%) 0.082
   Coronary artery disease (CAD) 64 (44.8%) 11 (57.9%) 0.332
   Patent foramen ovale 14 (20.3%) 2 (25%) 0.668
   Intracranial arterial disease 46 (46.0%) 11 (68.8%) 0.111
   COPD 29 (20.3%) 4 (21.1%) 0.999
   Carotid disease
     <50% Stenosis 69 (48.3%) 11 (57.9%) 0.191
     50–70% Stenosis 18 (12.6%) 4 (21.1%)
     >70% Stenosis 8 (5.6%) 2 (10.5%)
   Tobacco use 30 (21.0%) 4 (21.1%) 0.999
   Alcohol use 47 (32.9%) 4 (21.1%) 0.431
   Seizure disorder 0 (0.0%) 1 (5.3%) 0.117
   Migraine 10 (7.0%) 2 (10.5%) 0.635
   Autoimmune disease 5 (3.5%) 0 (0.0%) 0.999
   Coagulation disorders 8 (5.6%) 0 (0.0%) 0.598
   History of cancer 33 (23.1%) 7 (36.8%) 0.255
   Kidney disease 33 (23.1%) 7 (36.8%) 0.255
   Currently on dialysis 1 (0.7%) 0 (0.0%) 0.999
   Psychiatric illness 43 (30.1%) 8 (42.1%) 0.302
   Antiplatelet use (pre-hospitalization) 93 (65.0%) 14 (73.7%) 0.608
   Oral anticoagulant (pre-hospitalization) 17 (11.9%) 2 (10.5%) 0.999
Imaging study results
   WMD¥ on MRI Fazekas score
     Low 47 (43.1%) 5 (27.8%) 0.076
     Moderate 32 (29.4%) 6 (33.3%)
     Severe 18 (16.5%) 7 (38.9%)
§ABCD2 score
    ≤ 3 58 (40.6%) 5 (26.3%) 0.318
   3 < 85 (59.4%) 14 (73.7%)
§

ABCD2, (Age, Blood pressure, Clinical, Duration, Diabetes).

PAF, Paroxysmal Atrial Fibrillation.

COPD, Chronic Obstructive Pulmonary Disease;

¥

WMD, White Matter Disease.