Table 4.
Univariate analysis: composite outcome and associated factors among patients with DWI-neg TIA and DWI-pos TIA.
| Negative outcome event N = 143 | Positive outcome event N = 19 | P-Value | |
|---|---|---|---|
| Demographic Information | |||
| Gender (% of males) | 72 (50.3%) | 12 (63.2%) | 0.336 |
| Age, mean ± SD | 73.1 ± 12.8 | 80.4 ± 8.5 | 0.017* |
| Past medical history | |||
| Diabetes mellitus | 45 (31.5%) | 9 (47.4%) | 0.198 |
| Hypertension | 120 (83.9%) | 19 (100%) | 0.078 |
| Atrial fibrillation, PAF†, flutter | 25 (20.3%) | 5 (26.3%) | 0.553 |
| Hyperlipidemia | 126 (88.1%) | 18 (94.7%) | 0.698 |
| Previous history of stroke | 36 (25.2%) | 8 (41.2%) | 0.167 |
| Previous history of TIA | 36 (25.2%) | 5 (26.3%) | 0.999 |
| Peripheral vascular disease | 19 (13.3%) | 6 (31.6%) | 0.082 |
| Coronary artery disease (CAD) | 64 (44.8%) | 11 (57.9%) | 0.332 |
| Patent foramen ovale | 14 (20.3%) | 2 (25%) | 0.668 |
| Intracranial arterial disease | 46 (46.0%) | 11 (68.8%) | 0.111 |
| COPD‡ | 29 (20.3%) | 4 (21.1%) | 0.999 |
| Carotid disease | |||
| <50% Stenosis | 69 (48.3%) | 11 (57.9%) | 0.191 |
| 50–70% Stenosis | 18 (12.6%) | 4 (21.1%) | |
| >70% Stenosis | 8 (5.6%) | 2 (10.5%) | |
| Tobacco use | 30 (21.0%) | 4 (21.1%) | 0.999 |
| Alcohol use | 47 (32.9%) | 4 (21.1%) | 0.431 |
| Seizure disorder | 0 (0.0%) | 1 (5.3%) | 0.117 |
| Migraine | 10 (7.0%) | 2 (10.5%) | 0.635 |
| Autoimmune disease | 5 (3.5%) | 0 (0.0%) | 0.999 |
| Coagulation disorders | 8 (5.6%) | 0 (0.0%) | 0.598 |
| History of cancer | 33 (23.1%) | 7 (36.8%) | 0.255 |
| Kidney disease | 33 (23.1%) | 7 (36.8%) | 0.255 |
| Currently on dialysis | 1 (0.7%) | 0 (0.0%) | 0.999 |
| Psychiatric illness | 43 (30.1%) | 8 (42.1%) | 0.302 |
| Antiplatelet use (pre-hospitalization) | 93 (65.0%) | 14 (73.7%) | 0.608 |
| Oral anticoagulant (pre-hospitalization) | 17 (11.9%) | 2 (10.5%) | 0.999 |
| Imaging study results | |||
| WMD¥ on MRI Fazekas score | |||
| Low | 47 (43.1%) | 5 (27.8%) | 0.076 |
| Moderate | 32 (29.4%) | 6 (33.3%) | |
| Severe | 18 (16.5%) | 7 (38.9%) | |
| §ABCD2 score | |||
| ≤ 3 | 58 (40.6%) | 5 (26.3%) | 0.318 |
| 3 < | 85 (59.4%) | 14 (73.7%) | |
ABCD2, (Age, Blood pressure, Clinical, Duration, Diabetes).
PAF, Paroxysmal Atrial Fibrillation.
COPD, Chronic Obstructive Pulmonary Disease;
WMD, White Matter Disease.