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. 2019 Mar 27;9:186. doi: 10.3389/fonc.2019.00186

Table 3.

This table depicts all of the variables that were found to be statistically significantly associated with longer or shorter TT in the five studies that reported this analysis.

Association Variable P value
Han et al. (27) Shorter TT Biopsy only 0.006
Longer TT Younger age 0.02
Louvel et al. (28) Shorter TT Carmustine wafer implantation <0.001
Longer TT RPA class 5–6
Neurologic deficit
Post-operative seizures
<0.001
<0.001
0.049
Osborn et al. (30) Shorter TT Non-academic treatment facility
White race
Larger tumor size
STR (vs. GTR)
0.002
<0.001
<0.001
<0.001
Wang et al. (33) Shorter TT Older age
Lower KPS
Biopsy only
Higher RPA class
RT technique 3D conformal or 2D
0.006
<0.001
<0.001
<0.001
0.007
Pollom et al. (31) Shorter TT Black/African American race
Medicaid/Gov't insurance/no insurance Metropolitan area
> 50 miles from treatment facility
0.006
0.001
0.003
0.05
Longer TT Higher income 0.03

TT, treatment time; RPA, recursive partitioning analysis; STR, sub-total resection; GTR, gross total resection; KPS, Karnofsky Performance Status; RT, radiation therapy.