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. 2019 Mar 27;10:583. doi: 10.3389/fimmu.2019.00583

Table 1.

Genetic associations of Tnfsf15 gene with susceptibility and phenotype of IBD.

Polymorphism Ethnicity Susceptibility/Phenotype References
rs3810936 Asian, Caucasian
Asian
CD
UC
(6)
rs6478108 Asian, Caucasian

Asian, Caucasian
Asian
CD

UC
CD B2/B3
(6)
(7)
(8)
(9)
rs4979462 Asian CD (6)
rs6478109 Asian, Caucasian


Asian
CD


UC
(6)
(7)
(10)
(6)
rs7848647 Asian, Caucasian
Asian
Caucasian, Asian
CD
UC
CD early onset
(6)

(7, 11)
rs7869487 Asian, Caucasian CD (6)
rs4263839 Caucasian
Caucasian
Asian
Colonic CD location
Bowel resection
CD, B2/B3
(12)
(13)
(14)
rs4574921 Asian CD B3p (9)
rs11554257 Caucasian MR-UC (15)
rs3810936 Asian
Asian
Asian
Severe CD
CD
CD B3p
(16)
(17)
(7)
rs4246905 Asian IBD (18)

MR, Medically refractory; B2, B3, p, Montreal classification indicators for Crohn's disease.