Figure 4.

The antibacterial properties of ciprofloxacin delivered by a fibrin hydrogel compared to ciprofloxacin solution. The inhibition zone of 150 and 1500 μg/ml ciprofloxacin delivered by fibrin hydrogel were tested against Streptococcus mutans, Enterococcus faecalis, and Streptococcus sobrinus. Likewise, the standard ciprofloxacin solutions prepared in TBS at the same concentration were verified in parallel. Only TBS, fibrin hydrogel, and calcium hydroxide were loaded into the agar as the control. TBS: tris-buffered saline solution, * p-value < 0.05.