Table 1.
Characteristics of patients with granulomatosis with polyangiitis (GPA).
| Number of patients | 9 | |
|---|---|---|
| Age (years): | min – max | 24–68 |
| Median (IQR) | 57 (50–64) | |
| Gender | Female | 4 |
| Male | 5 | |
| Smoking | Yes | 0 |
| No | 9 | |
| Disease duration (years) (IQR) | 2 (1–6) | |
| GPA manifestation (no. of cases) | ||
| Lungs | 7 | |
| Kidney | 5 | |
| Skin | 5 | |
| Joints | 3 | |
| Peripheral nervous system | 1 | |
| GPA activity (no. of cases) | ||
| Remission | 6 | |
| Exacerbation | 1 | |
| Currently diagnosed | 2 | |
| Treatment (no. of cases) | ||
| Glucocorticosteroids (GCs) | 2 | |
| Azathioprine | 2 | |
| Cyclophosphamide + GCs | 3 | |
| Methotrexate + GCs | 1 | |
| Rituximab | 2 | |
| ANCA titres1 (min–max) | 1:10–1:1280 | |
| PR3 (IU/ml)1 Mean (min–max) | 87 (4–156) | |
| anti-PR3 (IU/ml)1 Mean (min–max) | 49 (<0.4–156) | |
Footnote:1 highest values during disease course.
Abbreviations: ANCA – anti-neutrophil cytoplasmic antibodies; anti-PR3 – anti-proteinase 3 antibodies; PR3 – proteinase.