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. 2019 Apr 3;39(14):2762–2773. doi: 10.1523/JNEUROSCI.2260-18.2019

Table 1.

Summary of statistical tests

Figure Test Statistical value p-value n (no. of animals) Post hoc comparisons
Groups compared Mean 1 Mean 2 Significance
2C One-way ANOVA F(3,22) = 16.68 <0.0001 7 (control) Control vs low RhebCA 95.6 127.8 *
8 (low RhebCA) Control vs int RhebCA 95.6 143.7 **
6 (int RhebCA) Control vs high RhebCA 95.6 180.6 ****
5 (high RhebCA) Low vs int RhebCA 127.8 143.7 ns
Low vs high RhebCA 127.8 180.6 **
Int vs high RhebCA 143.7 180.6 *
2E One-way ANOVA F(3,22) = 14.92 <0.0001 7 (control) Control vs low RhebCA 88.9 156.4 **
8 (low RhebCA) Control vs int RhebCA 88.9 143.9 *
6 (int RhebCA) Control vs high RhebCA 88.9 207.9 ****
5 (high RhebCA) Low vs int RhebCA 156.4 143.9 ns
Low vs high RhebCA 156.4 207.9 *
Int vs high RhebCA 143.9 207.9 *
2F Pearson's product–moment r = 0.8501 <0.0001 7 (control)
    correlation 8 (low RhebCA)
6 (int RhebCA)
5 (high RhebCA)
2H One-way ANOVA F(3,22) = 284.6 <0.0001 7 (control) Control vs low RhebCA 82.3 232.9 ****
8 (low RhebCA) Control vs int RhebCA 82.3 390.9 ****
6 (int RhebCA) Control vs high RhebCA 82.3 486.0 ****
5 (high RhebCA) Low vs int RhebCA 232.9 390.9 ****
Low vs high RhebCA 232.9 486.0 ****
Int vs high RhebCA 390.9 486.0 ****
2I Pearson's product–moment r = 0.8257 <0.0001 7 (control)
    correlation 8 (low RhebCA)
6 (int RhebCA)
5 (high RhebCA)
3D One-way ANOVA F(3,22) = 17.77 <0.0001 7 (control) Control vs low RhebCA 99.6 94.9 ns
8 (low RhebCA) Control vs int RhebCA 99.6 56.0 ****
6 (int RhebCA) Control vs high RhebCA 99.6 62.3 ***
5 (high RhebCA) Low vs int RhebCA 94.9 56.0 ***
Low vs high RhebCA 94.9 62.3 **
Int vs high RhebCA 56.0 62.3 ns
3F Two-way repeated- Interaction <0.0001 7 (control) See graph for relevant significant
    measures ANOVA F(27,198) = 7.371 8 (low RhebCA)     post hoc comparisons
Row effect: F(9,198) = 42.96 <0.0001 6 (int RhebCA)
Column effect: F(3,22) = 0.6691 0.5800 5 (high RhebCA)
Subjects (matching): F(22,198) = 6.304e-006 >0.9999
4B Spearman's rank–order r = 0.8709 <0.0001 7 (control)
    correlation 8 (low RhebCA)
7 (int RhebCA)
12 (high RhebCA)
4C Spearman's rank–order r = 0.6818 0.0018 8 (low RhebCA)
correlation 6 (int RhebCA)
4 (high RhebCA)
4D Spearman's rank–order r = 0.8693 <0.0001 8 (low RhebCA)
correlation 6 (int RhebCA)
4 (high RhebCA)
4E Mann-Whitney U U = 15 0.0208 7 (int RhebCA)
12 (high RhebCA)
4F Mann-Whitney U U = 27 0.4240 6 (int RhebCA)
12 (high RhebCA)
5A One-way ANOVA F(3,22) = 4.783 0.0103 7 (control) Control vs low RhebCA 74.4 64.5 ns
8 (low RhebCA) Control vs int RhebCA 74.4 138.5 *
6 (int RhebCA) Control vs high RhebCA 74.4 88.6 ns
5 (high RhebCA) Low vs int RhebCA 64.5 138.5 **
Low vs high RhebCA 64.5 88.6 ns
Int vs high RhebCA 138.5 88.6 ns
5B Spearman's rank–order r = 0.4294 0.0754 8 (low RhebCA)
    correlation 6 (int RhebCA)
4 (high RhebCA)
6B One-way ANOVA F(2,18) = 6.166 0.0091 7 (control) Control vs low RhebCA 131.7 144.7 ns
8 (low RhebCA) Control vs int RhebCA 131.7 167.1 **
6 (int RhebCA) Low vs int RhebCA 144.7 167.1 ns
6C Spearman's rank–order r = 0.5502 0.0441 8 (low RhebCA)
    correlation 6 (int RhebCA)
6D Two-way repeated- Interaction: 0.0414 7 (control) Ipsi-contra
    measures ANOVA F(2,16) = 3.913 8 (low RhebCA) Control 131.7 136.0 ns
Row effect: 0.0494 4 (int RhebCA) Low 144.7 138.2 ns
    F(1,16) = 4.522 Intermediate 179.3 163.5 *
Column effect: 0.0006 Ipsi
    F(2,16) = 12.05 Control vs low 131.7 144.7 ns
Subjects (matching): 0.0022 Control vs int 131.7 179.3 ****
    F(16,16) = 4.522 Low vs int 144.7 179.3 ***
Contra
Control vs low 136.0 138.2 ns
Control vs int 136.0 163.5 **
Low vs int 138.2 163.5 *
6E One-way ANOVA F(2,18) = 7.472 0.0043 7 (control) Control vs low RhebCA 49.7 51.6 ns
8 (low RhebCA) Control vs int RhebCA 49.7 72.0 **
6 (int RhebCA) Low vs int RhebCA 51.6 72.0 *

*p < 0.05,

**p < 0.01,

***p < 0.001,

****p < 0.0001.