Skip to main content
. 2019 Apr 3;39(14):2620–2634. doi: 10.1523/JNEUROSCI.2029-18.2019

Figure 5.

Figure 5.

NMDA-induced sodium transients. A, Sodium transients induced by three consecutive puff applications of NMDA (0.5 mm/50 ms) in somata of individual astrocytes (left) and adjacent neurons (right) in the cortex (top traces) and hippocampus (bottom traces). B, Effect of AP5 (100 μm) on NMDA-induced sodium transients in astrocytes and adjacent neurons in cortex (top traces) and hippocampus (bottom traces). C, Histograms represent mean ± SEM peak amplitudes of astrocyte and neuronal sodium transients in response to NMDA in control and with addition of AP5 (100 μm) in the cortex and hippocampus. D, Multiphoton imaging of sodium transients induced by NMDA (0.5 mm/50 ms) in astrocytes and adjacent neurons in the cortex (left traces) and hippocampus (right traces). Right, Histograms represent mean ± SEM peak amplitudes of sodium changes in astrocytes (top) and neurons (bottom) in cortex (c) and hippocampus (h) in response to NMDA as determined by multiphoton imaging. ***p < 0.001. **0.001 ≤ p < 0.01.