Table 1.

[¹¹C]raclopride BP_ND in ROIs

	[11C]raclopride BPND		Paired t test
	Placebo	Methylphenidate	Change, %	t	p	dz
Composite ROI	0.362 ± 0.035	0.354 ± 0.038	2.29	2.26	0.03	0.38
Bilateral amygdala	0.408 ± 0.043	0.399 ± 0.046	2.10	2.08	0.05	0.38
R amygdala	0.400 ± 0.044	0.397 ± 0.049	0.67	0.59	0.56	0.10
L amygdala	0.417 ± 0.046	0.403 ± 0.047	3.20	2.64	0.01	0.48
Bilateral rACC	0.326 ± 0.041	0.318 ± 0.041	2.10	1.55	0.13	0.27
R rACC	0.332 ± 0.043	0.324 ± 0.045	1.75	1.13	0.27	0.20
L rACC	0.323 ± 0.046	0.314 ± 0.044	2.29	1.68	0.10	0.30
Bilateral occipital	0.191 ± 0.038	0.194 ± 0.036	−0.02	0.82	0.42	0.15
R occipital	0.195 ± 0.039	0.201 ± 0.038	−0.04	1.67	0.11	0.31
L occipital	0.188 ± 0.042	0.187 ± 0.038	0.00	0.33	0.75	0.06
Whole striatum	3.347 ± 0.228	3.044 ± 0.225	8.98	10.65	<0.001	2.63
Bilateral DCA	3.039 ± 0.248	2.821 ± 0.246	7.13	9.22	<0.001	1.70
R dorsal caudate	3.029 ± 0.243	2.812 ± 0.260	7.16	8.51	<0.001	1.58
L dorsal caudate	3.050 ± 0.262	2.831 ± 0.244	7.05	7.70	<0.001	1.42
Bilateral DPUT	3.867 ± 0.276	3.471 ± 0.305	10.15	8.98	<0.001	1.66
R dorsal putamen	3.875 ± 0.275	3.478 ± 0.312	10.18	8.78	<0.001	1.62
L dorsal putamen	3.859 ± 0.282	3.465 ± 0.303	10.12	9.11	<0.001	1.65
Bilateral VST	2.605 ± 0.220	2.400 ± 0.229	8.00	11.79	<0.001	2.07
R ventral striatum	2.541 ± 0.224	2.335 ± 0.221	8.04	10.37	<0.001	1.84
L ventral striatum	2.667 ± 0.257	2.457 ± 0.264	7.83	8.89	<0.001	1.63
Bilateral hippocampus	0.308 ± 0.030	0.307 ± 0.035	0.52	0.46	0.65	0.08
R hippocampus	0.302 ± 0.028	0.303 ± 0.035	−0.39	0.19	0.85	0.03
L hippocampus	0.314 ± 0.037	0.310 ± 0.039	0.97	0.77	0.45	0.14

BP_ND is reported as mean ± SD. Composite ROI is comprised of bilateral amygdala and rACC. ROIs were structurally-defined from each participant's anatomical FreeSurfer segmentation with the exception of striatal ROIs, which were manually segmented. R, Right; L, left.