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. 2019 Mar 13;51(1):45–53. doi: 10.3947/ic.2019.51.1.45

Table 3. Characteristics of the patients diagnosed with a true infection.

Case Gender Age Underlying Malignancy Specimen Diagnosis/Possible Source Presentation/Clinical Symptoms Prior Procedures CVC or Other Device Time to Diagnosis of Infectiona Antibiotic Treatment Other Treatment Intervention
1 M 55 Urothelial cancer Wound culture (deep abdominal wound) Abdominal-pelvic subcutaneous abscess Fever, chills, abdominal pain Repair of large ventral hernia with primary closure No 28 days Cephalexin for 14 days I&D of abdominal abscesses, Wound Vacuum placement
2 F 68 Poorly differentiated chordoma of the foot Superficial wound culture Below-knee amputation site soft tissue infection and fluid collection Pain and burning at prior amputation site Right below knee amputation No 8 months and 26 days Doxycycline and Ciprofloxacin for 14 days none
3 M 67 Prostate cancer Body fluid aspirate culture Pelvic abscess Fever, chills Robotic radical prostatectomy No 2 months and 14 days Linezolid for 14 days, followed by Sulfamethoxazole/Trimethoprim for 28 days CT-guided drainage of pelvic fluid collection
4 M 29 Dermatofibrosarcoma Body fluid aspirate culture Left groin fluid collection at prior surgical site Left groin pain Inguinal mass resection No 23 days Amoxicillin/Clavulanate for 14 days US-guided fluid collection aspiration
5 M 73 Metastatic penile cancer Body fluid aspirate culture Left thigh fluid collection Left thigh erythema and pain Total urethrectomy, peritoneal urethrostomy, bilateral groin lymph node dissection Port 1 month and 29 days Cephalexin for 28 days US-guided drainage
6 M 47 Melanoma of the thigh Body fluid aspirate culture Left thigh abscess Fever, pain at abscess site Left thigh melanoma excision with groin LN dissection No 2 months and 11 days Vancomycin and Ampicillin/Sulbactam for 3 days, transitioned to oral doxycycline on discharge for 14 more days CT-guided drainage of abscess
7 F 41 Melanoma of the buttock Body fluid culture (JP drain) Groin surgical site infection (wound infection/cellulitis) Fever, Purulent drainage from wound Melanoma site resection and right groin lymphadenectomy No 31 days Amoxicillin/Clavulanate and ciprofloxacin for 10 days JP drainage
8 M 64 AML, s/p allogeneic HSCT Blood culture (one culture positive) Bacteremia, possibly CVC-associated Fatigue, leukopenia None Yes (Hickman catheter) N/A Vancomycin IV for 10 days CVC removal
9 F 78 Renal cell carcinoma Blood Culture (one culture positive, polymicrobial) Bacteremia, from prior surgical wound infection/dehiscence Wound dehiscence Spinal instrumentation and fusion No 1 month and 18 days Vancomycin IV and oral Ciprofloxacin for 42 days Spinal hardware removal
10 M 49 Germ cell testicular cancer Urine culture UTI Dysuria, UA pyuria WBC >100/hpf, abdominal pain None Left ureteral stent 3 months and 27 days Ciprofloxacin for 14 days none
11 M 64 Renal cell carcinoma Urine culture UTI Urinary retention, UA pyuria WBC >100/hpf Left open radical nephrectomy Intermittent straight catheterizations 26 days Ciprofloxacin for 10 days none
12 F 59 Metastatic breast cancer Urine culture UTI UTI symptoms, not other specified, UA pyuria WBC >100/hpf none Implantable port N/A Nitrofurantoin for 14 days none
13 F 77 Metastatic colorectal cancer Urine culture UTI Urinary frequency, pain with urination, UA WBC >100/hpf none none N/A Trimethoprim-sulfamethoxazole for 14 days none
14 F 79 Chronic lymphocytic leukemia Urine culture UTI Frequent urination, UA WBC >100/hpf none none N/A Ciprofloxacin for 7 days none

aDuration between the date of surgical procedure performed and the date of infection occurred and culture taken.

CVC, central venous catheter; M, male; F, female; CT, computed tomography; US, ultrasound; JP, Jackson-Pratt drain; AML, acute myelogenous luekemia; s/p, status post; HSCT, hematopoietic stem cell transplant; N/A, not applicable; UTI, urinary tract infection; UA, urinalysis; WBC, white blood cell; hpf, high-power field.