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. 2019 Mar 26;51(1):35–44. doi: 10.3947/ic.2019.51.1.35

Table 5. Clinical characteristics and endoscopic findings according to combination antiretroviral therapy duration in the patients with good adherence.

≤6 M (N = 58) >6 M ~ ≤5 Y (N = 60) >5 Y ~ ≤10 Y (N = 55) >10 Y (N = 27) P-value
Age, years, median (IQR) 47.5 (39.8–55.5) 53 (43.3–60) 55 (50–62) 59 (54–67) <0.001
Male sex, No. (%) 49 (84.5) 53 (88.3) 48 (87.3) 23 (85.2) 0.931
CD4 cell count/mm3, median (IQR) 107.5 (36.5–296.0) 457 (262.5–610.8) 612 (464.5–793.3) 595 (530–852) <0.001
CD4 cell count <200/ mm3, No. (%) 33 (56.9) 7 (11.7) 2 (3.6) 0 (2.9) <0.001
HIV RNA virus, log/mL, median (IQR) 5 (2.8–5.5) 0 (0–0) 0 (0–0) 0 (0–0) <0.001
The median observation period, years (IQR) 0.1 (0–0.3) 3.0 (1.5–4.2) 7.6 (5.2–18.8) 12.0 (11.2–13.8) <0.001
The median cART period, years (IQR) 0 (0–0.1) 2.5 (1.2–3.6) 6.7 (5.1–9.7) 11.5 (10.9–13.0) <0.001
Endoscopic finding, No. (%)
Opportunistic infection 16 (27.6) 5 (8.3) 0 (0.0) 2 (7.4) <0.001
Esophagus
Reflux esophagitis 15 (25.9) 16 (26.7) 20 (36.4) 4 (14.8) 0.217
Esophageal candidiasis 14 (24.1) 5 (8.3) 0 (0.0) 2 (7.4) <0.001
Esophageal ulcer 8 (13.8) 3 (5.0) 1 (1.8) 0 (0.0) 0.035
CMV esophagitis 4 (6.9) 0 (0.0) 0 (0.0) 0 (0.0) 0.020
Stomach
Atrophic gastritis 26 (44.8) 32 (53.3) 39 (70.9) 22 (81.5) 0.002
Erosive gastritis 10 (17.2) 13 (21.7) 20 (36.4) 10 (37.0) 0.056
Erythematous gastritis 22 (37.9) 19 (31.7) 13 (23.6) 4 (14.8) 0.119
Intestinal metaplasia 11 (19.0) 15 (25.0) 19 (34.5) 8 (29.6) 0.293
Gastric ulcer 8 (13.8) 4 (6.7) 7 (12.7) 3 (11.1) 0.619
Gastric cancer 0 (0.0) 1 (1.4) 1 (1.7) 1 (2.9) 0.486
Kaposi sarcoma 1 (1.7) 0 (0.0) 0 (0.0) 0 (0.0) 1.000
Duodenum
Duodenal ulcer 1 (1.7) 1 (1.7) 1 (1.8) 2 (7.4) 0.467
Duodenitis 7 (12.1) 3 (5.0) 3 (5.0) 0 (0.0) 0.202

M, month; Y, year; IQR, interquartile range; HIV, human immunodeficiency virus; cART, combination antiretroviral therapy; CMV, cytomegalovirus.