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. Author manuscript; available in PMC: 2019 Apr 3.
Published in final edited form as: Invest New Drugs. 2010 Sep 7;30(1):90–97. doi: 10.1007/s10637-010-9520-5

Fig. 5.

Fig. 5

a SW620 xenograft tumor growth. Open circles represent animals treated with vehicle control only (n=10). Open squares represent animals treated with 50 mg/kg LP-261, po, BID, daily (n=6). Filled circles represent animals treated with 15 mg/kg paclitaxel, IV, once weekly (n=6). Animals were treated for 24 days except for control animals sacrificed at day 14. b) Change in SW620 xenograft tumor volume with vehicle control (open circles), 12.5 mg/kg LP-261 po daily, 5×/week (filled squares), 5 mg/kg bevacizumab ip twice weekly (filled circles) or the combination (open squares).All animals were treated for 24 days. Each marker represents the mean (n≥6)±S.D. percentage change in tumor volume since the start of treatment