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. 2019 Feb 28;16:284–294. doi: 10.1016/j.omtn.2019.02.021

Figure 8.

Figure 8

Schematic Diagram for the Potential Role of miR-134-5p in the Pathogenesis of Thoracic Aortic Dissection

miR-134-5p might suppress ITGB1 expression by affecting the binding of 3′ UTR. This process was involved in AoSMC phenotypic switch and metastasis. As a result, miR-134-5p repressed the vessel remodeling and thoracic aortic dissection via regulating ITGB1 expression.