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. 2019 Mar 27;10:200. doi: 10.3389/fphar.2019.00200

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Copyright © 2019 Ladomersky, Scholtens, Kocherginsky, Hibler, Bartom, Otto-Meyer, Zhai, Lauing, Choi, Sosman, Wu, Zhang, Lukas and Wainwright.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Progressive aging is associated with an increased rate of cancer incidence and mortality. (A) Life expectancy from the Center for Disease Control and Prevention (CDC) database for an average lifespan in the United States between the years 1975 and 2015. (B) Population data from the Surveillance, Epidemiology, and Ends Results (SEER) database representing the total number of elderly human subjects (ages ≥65) divided by the total population in the United States for the years 1975, 1995, and 2015. (C) Incidence and (D) mortality rates from the SEER database for all malignancies in the years 1975, 1995, and 2015. Rates are defined as number of cases and deaths, respectively, divided by the population in each age category and multiplied by 100,000 people (per 100,000).