Table 1.
Api preserved reduced the levels of lipid peroxidation, the activities of antioxidant enzymes, and the ferric reducing antioxidant power in the myocardium against SI/R injury.
| Groups | MDA content (nmol/g tissue) | CAT activity (U/g tissue) | SOD activity (U/g tissue) | GPx activity (U/g tissue) | FRAP (mmol Fe2+/L) |
|---|---|---|---|---|---|
| Control | 31.6 ± 2.3 | 15.5 ± 1.2 | 85.1 ± 4.5 | 23.1 ± 1.5 | 5.29 ± 0.26 |
| SI/R | 135.2 ± 12.8a | 3.8 ± 0.4a | 20.6 ± 2.3a | 6.1 ± 0.5a | 1.32 ± 0.04a |
| Api + SI/R | 51.5 ± 4.8b | 13.1 ± 1.1b | 63.1 ± 4.2b | 18.2 ± 1.5b | 4.61 ± 0.28b |
| Api + SI/R + GSI | 66.3 ± 6.2 | 11.9 ± 1.2 | 60.4 ± 3.9 | 17.1 ± 1.8 | 3.81 ± 0.23 |
| SI/R + GSI | 82.1 ± 7.2 | 9.8 ± 0.8 | 57.3 ± 4.1 | 16.0 ± 1.5 | 1.53 ± 0.09 |
Values are presented as mean ± S.E.M. of five individual experiments. (a) p < 0.01 vs. control group; (b) p < 0.01 vs. SI/R group.