Table 3.
Laboratory and clinical course of patients with systemic loxoscelism.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 | Patient 9 | |
|---|---|---|---|---|---|---|---|---|---|
| Initial WBC count (x103/mL) | 5.6 | 40.7 | 17.1 | 44.8 | 14 | 11.4 | 13 | 9.3 | 9.3 |
| Peak WBC count (x103/mL) | 15.9 | 50.9 | 65 | 44.8 | 17.3 | 29.4 | 16 | 50.2 | 13.4 |
| Lowest platelet (x103/mL) | 136 | 365 | 152 | 179 | 136 | 124 | 117 | 144 | 320 |
| Initial Hgb (g/dL) | 10.1 | 5.3 | 3.5 | 11.7 | 4.7 | 12 | 8.8 | 9.3 | 14.2 |
| Lowest Hgb (g/dL) | 6.3 | 5.3 | 3.5 | 8.2 | 4.7 | 4.4 | 6.0 | 7.6 | 4.8 |
| Onset of hemolysis relative to bite (days) | 5 | 3 | 4 | 5 | 3 | 7 | 6 | 1 | 6 |
| Hgb at discharge (g/dL) | 7.5 | 8.2 | 8.8 | 9.1 | 11.1 | 6.9 | 7.8 | 12 | 9.1 |
| Peak Reticulocyte count (%) | 3.9 | 10.8 | 0.6 | 3.93 | 1.6 | 2.6 | 2.7 | 10.5 | 13.2 |
| Haptoglobin (mg/dL) | <8 | <8 | Not measured | Not measured | Not measured | 67 | Not measured | 158 | 197 |
| Peak total bilirubin | 16.2 | 5.2 | 39.2 | 0.5 | 4.3 | 4.3 | 2.4 | 21 | 5.6 |
| LDH at admission (U/L) | 1146 | 953 | 2337 | 328 | 1633 | 320 | 261 | 566 | 549 |
| DAT (Surface IgG) | negative | negative | positive | negative | negative | positive | negative | positive | positive |
| DAT (Surface C3) | negative | negative | positive | negative | negative | positive | negative | positive | positive |
| Hospital admission | Med-Surg | ICU | ICU | ICU | Med-Surg | Med-Surg | ICU | Med-Surg | Med-Surg |
| Transfusion (pRBC units) | 1 | 3 | 4 | 0 | 7 | 3 | 3 | 2 | 2 |
| Corticosteroid use | No | No | Yes | Yes | No | No | No | Yes | Yes |
| IVIg use | No | No | No | No | No | No | No | No | Yes |
| Incision and drainage | No | Yes | No | No | No | Yes | Yes | Yes | No |
Abbreviations: WBC, White Blood Cell; LDH, Lactate Dehydrogenase; DAT, Direct Antiglobulin Test; pRBCs, packed Red Blood Cells.