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. 2019 Mar 27;10:575. doi: 10.3389/fimmu.2019.00575

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Copyright © 2019 Tay, Lim, Leong, Thiam, Tan, Torta, Narayanaswamy, Wenk and Angeli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proliferation and entry of lymphocytes in apoE^−/− mice are not affected by dyslipidemia. (A) LNs sections from 22 to 28 weeks old WT and apoE^−/− mice were double stained for TCRβ and Ki-67. Box demarcates B cell follicle (B) Short term homing experiments were performed to assess the entry of CD45.1 WT lymphocytes, T or B cells into LNs from CD45.2 WT and apoE^−/− recipient mice. (C) The entry of CD45.2 CFSE-labeled WT or apoE^−/− lymphocytes, T or B cells into WT LNs was examined. n = 9 mice per group. *p < 0.05; ***p < 0.0005.