Table 1.
Study Population Demographics
| Adult Subjects | Elderly Subjects | |||
|---|---|---|---|---|
| (Age 18–64 y, n = 979) | (Age ≥65 y, n = 1393) | |||
| Full-Dose | Half-Dose | Full-Dose | Half-Dose | |
| (n = 488) | (n = 491) | (n = 700) | (n = 693) | |
| Age, mean ± SD, y | 39.0 ± 13.7 | 38.4 ± 14.2 | 71.2 ± 5.1 | 70.7 ± 4.7 |
| Male, No. (%) | 203 (42) | 232 (47) | 293 (42) | 275 (40) |
| Weight, mean ± SD, kg | 74.1 ± 15.1 | 73.5 ± 16.3 | 71.0 ± 15.9 | 71.4 ± 16.2 |
| Height, mean ± SD, cm | 167.8 ± 10.5 | 168.5 ± 11.0 | 164.1 ± 10.7 | 163.5 ± 10.9 |
| BMI, mean ± SD, kg/m2 | 26.2 ± 4.3 | 25.7 ± 4.3 | 26.1 ± 4.0 | 26.5 ± 4.2 |
| Previous influenza vaccination, No. (%) | 118 (24) | 119 (24) | 429 (61) | 419 (60) |
| Influenza vaccination ≤12 mo,a No. (%) | 98 (20) | 95 (19) | 146 (21) | 137 (20) |
| White, No. (%) | 291 (60) | 290 (59) | 445 (64) | 444 (64) |
| Asian, No. (%) | 93 (19) | 96 (20) | 240 (34) | 237 (34) |
| Black/African American, No. (%) | 97 (20) | 99 (20) | 10 (1) | 10 (1) |
| American Indian/Alaska Native, No. (%) | 2 (<1) | 1 (<1) | 2 (<1) | 0 |
| Native Hawaiian/Pacific Islander, No. (%) | 0 | 1 (<1) | 0 | 0 |
Full-dose: 7.5 µg of aH5N1c antigen + 0.25 mL of MF59 adjuvant per dose; Half-dose: 3.75 µg of aH5N1c antigen + 0.125 mL of MF59 adjuvant per dose.
Abbreviation: BMI, body mass index; SD, standard deviation.
aTwelve months before enrollment in the study.