Table 3.
Histological parameters using Banff 97 classification (ah, ci, ct, cv and cg) and karpinski score and association with eGFR at 5 years.
| Histological parameters | n | eGFR <35ml/min | eGFR >35ml/min | p Univariate | p Multivariate |
|---|---|---|---|---|---|
| Glomerular sclerosis | |||||
| 0% | 15 | 2.9% | 14.7% | .074 | .045 |
| 10% | 72 | 50.0% | 57.9% | – | – |
| 10–19% | 32 | 38.2% | 20.0% | – | – |
| >20% | 10 | 8.8% | 7.4% | – | – |
| Interstitial fibrosis | |||||
| 0–19% | 25 | 18.8% | 20.0% | .642 | .103 |
| 20–29% | 59 | 40.6% | 48.4% | – | – |
| >30% | 43 | 40.6% | 31.6% | – | – |
| Arteriolar hyalinosis (ah) | |||||
| 0 | 41 | 21.2% | 36.6% | .379 | .182 |
| 1 | 62 | 57.6% | 46.2% | – | – |
| 2 | 22 | 21.2% | 16.1% | – | – |
| 3 | 1 | 0.0% | 1.1% | – | – |
| Chronic interstitium (ci) | |||||
| 0 | 3 | 0.0% | 3.2% | .510 | .119 |
| 1 | 78 | 55.9% | 62.1% | – | – |
| 2 | 48 | 44.1% | 34.7% | – | – |
| Chronic tubules (ct) | |||||
| 0 | 8 | 0.0% | 8.4% | .125 | .782 |
| 1 | 113 | 97.1% | 84.2% | – | – |
| 2 | 8 | 2.9% | 7.4% | – | – |
| Chronic vessels (cv) | |||||
| 0 | 45 | 21.2% | 43.7% | .038 | .054 |
| 1 | 69 | 69.7% | 52.9% | – | – |
| 2 | 6 | 9.1% | 3.4% | – | – |
| Chronic glomerulopathy (cg)a | |||||
| 0 | 104 | 76.5% | 82.1% | .461 | .162 |
| 1 | 25 | 23.5% | 17.9% | ||
| Karpinskib | |||||
| 0–3 | 30 | 5.9% | 29.8% | .010 | .033 |
| 4–5 | 75 | 70.6% | 54.3% | ||
| 6–9 | 23 | 23.5% | 15.9% | ||
a
cg is graded 0–1 using Banff classification; however, there were no biopsies graded >1 in study cohort.
b
Karpinski score is graded 0–12; however, there were no biopsies graded >9 in study cohort.